Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity

Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity

Effects of fructose 1,6-bisphosphate (F-1,6-P2) towards <i>N</i>-methyl-<span style="font-variant: small-caps;">d</span>-aspartate NMDA excitotoxicity were evaluated in rat organotypic hippocampal brain slice cultures (OHSC) challenged for 3 h with 30 &#956;M NM...

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Bibliographic Details
Main Authors: Kamal M. Yakoub, Giacomo Lazzarino, Angela M. Amorini, Giuseppe Caruso, Concetta Scazzone, Marcello Ciaccio, Barbara Tavazzi, Giuseppe Lazzarino, Antonio Belli, Valentina Di Pietro
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
fructose-1,6-bisphosphate
<i>N</i>-methyl-<span style="font-variant: small-caps">d</span>-aspartate
excitotoxicity
energy metabolism
mitochondrial dysfunction
organotypic hippocampal brain slice cultures
Online Access:https://www.mdpi.com/1422-0067/20/9/2239

Internet

https://www.mdpi.com/1422-0067/20/9/2239

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