Quantitative Methods to Monitor RNA Biomarkers in Myotonic Dystrophy

Quantitative Methods to Monitor RNA Biomarkers in Myotonic Dystrophy

Abstract Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are human neuromuscular disorders associated with mutations of simple repetitive sequences in affected genes. The abnormal expansion of CTG repeats in the 3′-UTR of the DMPK gene elicits DM1, whereas elongated CCTG repeats in intron 1 of ZNF9...

Full description

Bibliographic Details
Main Authors: Marzena Wojciechowska, Krzysztof Sobczak, Piotr Kozlowski, Saam Sedehizadeh, Agnieszka Wojtkowiak-Szlachcic, Karol Czubak, Robert Markus, Anna Lusakowska, Anna Kaminska, J. David Brook
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24156-x

Internet

https://doi.org/10.1038/s41598-018-24156-x

Similar Items