Synthesis and phototoxicity of isomeric 7,9-diglutathione pyrrole adducts: Formation of reactive oxygen species and induction of lipid peroxidation

Pyrrolizidine alkaloids (PAs) are hepatotoxic, genotoxic, and carcinogenic in experimental animals. Because of their widespread distribution in the world, PA-containing plants are probably the most common poisonous plants affecting livestock, wildlife, and humans. Upon metabolism, PAs generate react...

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Bibliographic Details
Main Authors: Liang Ma, Hengqiang Zhao, Qingsu Xia, Lining Cai, Peter P. Fu
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Journal of Food and Drug Analysis
Subjects:
DHP
Online Access:http://www.sciencedirect.com/science/article/pii/S1021949815000745