Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis
Pro-inflammatory factors implicated for the onset of arthritis often have systematic effects, yet arthritis symptoms are mostly limited to the joints. Here the authors show that mechanical strain at the joints promotes the recruitment of monocyte and their differentiation into bone-eroding osteoclas...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-06933-4 |