Hypoxia: Progressive Multiple Myeloma and Its Therapy Resistance

This study critically reviews the role of hypoxia in the progression of Multiple Myeloma (MM)and its therapy resistance. It explains the existence and role played by Hypoxia Inducible Factors (HIF) including HIF-1α and HIF-β in tumor (MM) progression. These HIF are key transcription factors of hypo...

Full description

Bibliographic Details
Main Authors: Ogechi Charity Obayi, Emmanuella Ogbonna, Catherine Chinonye Eleje, Nwabueze Enukaorah Permsec Umerah
Format: Article
Language:English
Published: Research Center for Rational Use of Drugs (RCRUD) 2021-04-01
Series:Journal of Pharmaceutical Care
Subjects:
Online Access:https://jpc.tums.ac.ir/index.php/jpc/article/view/389