A generic standard additions based method to determine endogenous analyte concentrations by immunoassays to overcome complex biological matrix interference
Abstract We describe a novel generic method to derive the unknown endogenous concentrations of analyte within complex biological matrices (e.g. serum or plasma) based upon the relationship between the immunoassay signal response of a biological test sample spiked with known analyte concentrations an...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-17823-y |