Multimodality multiparametric imaging of early tumor response to a novel antiangiogenic therapy based on anticalins.

Anticalins are a novel class of targeted protein therapeutics. The PEGylated Anticalin Angiocal (PRS-050-PEG40) is directed against VEGF-A. The purpose of our study was to compare the performance of diffusion weighted imaging (DWI), dynamic contrast enhanced magnetic resonance imaging (DCE)-MRI and...

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Main Authors: Reinhard Meier, Rickmer Braren, Yvonne Kosanke, Johanna Bussemer, Frauke Neff, Moritz Wildgruber, Sarah Schwarzenböck, Annette Frank, Bernhard Haller, Andreas M Hohlbaum, Markus Schwaiger, Hendrik Gille, Ernst J Rummeny, Ambros J Beer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4011746?pdf=render