Impaired Coronary and Renal Vascular Function in Spontaneously Type 2 Diabetic Leptin-Deficient Mice.

Type 2 diabetes is associated with macro- and microvascular complications in man. Microvascular dysfunction affects both cardiac and renal function and is now recognized as a main driver of cardiovascular mortality and morbidity. However, progression of microvascular dysfunction in experimental mode...

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Main Authors: Helena U Westergren, Julia Grönros, Suvi E Heinonen, Tasso Miliotis, Karin Jennbacken, Alan Sabirsh, Anette Ericsson, Ann-Cathrine Jönsson-Rylander, Sara Svedlund, Li-Ming Gan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4476758?pdf=render