Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity

Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity

Summary: The mammary epithelial cell (MEC) system is a bilayered ductal epithelium of luminal and basal cells, maintained by a lineage of stem and progenitor populations. Here, we used integrated single-cell transcriptomics and chromatin accessibility analysis to reconstruct the cell types of the mo...

Full description

Bibliographic Details
Main Authors: Nicholas Pervolarakis, Quy H. Nguyen, Justice Williams, Yanwen Gong, Guadalupe Gutierrez, Peng Sun, Darisha Jhutty, Grace X.Y. Zheng, Corey M. Nemec, Xing Dai, Kazuhide Watanabe, Kai Kessenbrock
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Cell Reports
Subjects:
mammary stem cells
single-cell genomics
transcriptomics
chromatin accessibility
cellular heterogeneity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720312626

Internet

http://www.sciencedirect.com/science/article/pii/S2211124720312626

Similar Items