Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria.

BACKGROUND:Early secretory antigenic target-6 (ESAT-6) and culture filtrate protein-10 (CFP-10) are co-secreted proteins of Mycobacterium tuberculosis complex mycobacteria (includes M. bovis, the zoonotic agent of bovine tuberculosis) involved in phagolysosome escape of the bacillus and, potentially...

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Main Authors: W Ray Waters, Mitchell V Palmer, Brian J Nonnecke, Tyler C Thacker, D Mark Estes, Michelle H Larsen, William R Jacobs, Peter Andersen, James McNair, F C Minion, Konstantin P Lyashchenko, R Glyn Hewinson, H Martin Vordermeier, Randy E Sacco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2714177?pdf=render