ILC2 Cells Promote Th2 Cell Differentiation in AECOPD Through Activated Notch-GATA3 Signaling Pathway

ILC2 Cells Promote Th2 Cell Differentiation in AECOPD Through Activated Notch-GATA3 Signaling Pathway

This study is to investigate the capacity of type 2 innate lymphoid cells (ILC2s) in regulating the Th2 type adaptive immune response of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The study enrolled healthy people, stable chronic obstructive pulmonary disease (COPD) patien...

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Bibliographic Details
Main Authors: Min Jiang, Ren Cai, Jing Wang, Zheng Li, Dan Xu, Jing Jing, Fengbo Zhang, Fengsen Li, Jianbing Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
acute exacerbation of chronic obstructive pulmonary disease
Notch-GATA3 pathway
type 2 innate lymphoid cell
Th2 polarized
cell differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.685400/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.685400/full

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