A multi-step pathway for the establishment of sister chromatid cohesion.

The cohesion of sister chromatids is mediated by cohesin, a protein complex containing members of the structural maintenance of chromosome (Smc) family. How cohesins tether sister chromatids is not yet understood. Here, we mutate SMC1, the gene encoding a cohesin subunit of budding yeast, by random...

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Bibliographic Details
Main Authors: Mark Milutinovich, Elçin Unal, Chris Ward, Robert V Skibbens, Douglas Koshland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1779304?pdf=render