Rewiring of PDZ domain-ligand interaction network contributed to eukaryotic evolution.

Rewiring of PDZ domain-ligand interaction network contributed to eukaryotic evolution.

PDZ domain-mediated interactions have greatly expanded during metazoan evolution, becoming important for controlling signal flow via the assembly of multiple signaling components. The evolutionary history of PDZ domain-mediated interactions has never been explored at the molecular level. It is of gr...

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Bibliographic Details
Main Authors: Jinho Kim, Inhae Kim, Jae-Seong Yang, Young-Eun Shin, Jihye Hwang, Solip Park, Yoon Sup Choi, Sanguk Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3276551?pdf=render

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http://europepmc.org/articles/PMC3276551?pdf=render

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