Cyclodextrins and ternary complexes: technology to improve solubility of poorly soluble drugs

Cyclodextrins and ternary complexes: technology to improve solubility of poorly soluble drugs

Cyclodextrins (CDs) are cyclic oligosaccharides composed of D-glucopyranoside units linked by glycosidic bonds. Their main property is the ability to modify the physicochemical and biological characteristics of low-soluble drugs through the formation of drug:CD inclusion complexes. Inclusion complex...

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Bibliographic Details
Main Authors: Janisse Crestani de Miranda, Tércio Elyan Azevedo Martins, Francisco Veiga, Humberto Gomes Ferraz
Format: Article
Language:English
Published: Universidade de São Paulo 2011-12-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
SCiclodextrinas
Complexos ternários
Fármacos
Polímeros hidrossolúveis
Complexos de inclusão
Cyclodextrins
Ternary complexes
Drugs
Water-soluble polymers
Inclusion complexe
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400003

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400003

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