Radio-deoxynucleoside Analogs used for Imaging tk Expression in a Transgenic Mouse Model of Induced Hepatocellular Carcinoma
<p>Purpose: A group of radiolabeled thymidine analogs were developed as radio-tracers for imaging herpes viral thymidine kinase (HSV1-<i>tk</i>) or its variants used as reporter gene. A transgenic mouse model was created to express <i>tk</i> upon liver injury or natural...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2012-01-01
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| Series: | Theranostics |
| Online Access: | http://www.thno.org/v02p0597.htm |