Photothermogenetic inhibition of cancer stemness by near-infrared-light-activatable nanocomplexes

Cancer stem cells (CSCs) are known to induce chemotherapy resistance, and cause tumour relapse and metastasis. Here, the authors develop photoactive nanocarbon complexes with second near-infrared photothermal ability to target cancer cells overexpressing the receptor TRPV2 and show it to suppress CS...

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Bibliographic Details
Main Authors: Yue Yu, Xi Yang, Sheethal Reghu, Sunil C. Kaul, Renu Wadhwa, Eijiro Miyako
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17768-3