Role of Spinal Cord Akt-mTOR Signaling Pathways in Postoperative Hyperalgesia Induced by Plantar Incision in Mice

Role of Spinal Cord Akt-mTOR Signaling Pathways in Postoperative Hyperalgesia Induced by Plantar Incision in Mice

Poor postoperative pain (POP) control increases perioperative morbidity, prolongs hospitalization days, and causes chronic pain. However, the specific mechanism(s) underlying POP is unclear and the identification of optimal perioperative treatment remains elusive. Akt and mammalian target of rapamyc...

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Bibliographic Details
Main Authors: Bing Xu, Su-Su Liu, Jin Wei, Zi-Yin Jiao, Cheng Mo, Cheng-Mei Lv, Ai-Lan Huang, Qi-Bo Chen, Li Ma, Xue-Hai Guan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
the mammalian target of rapamycin kinase
protein kinase B
incisional pain
spinal dorsal corn
mice
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00766/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00766/full

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