Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors
The hypoxic tumor microenvironment is the major contributor of chemotherapy resistance in solid tumors. One of the key regulators of hypoxic responses within the cell is the hypoxia inducible factor-1α (HIF-1α) that is involved in transcription of genes promoting cell survival and chemotherapy resis...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2019-02-01
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| Series: | PeerJ |
| Subjects: | |
| Online Access: | https://peerj.com/articles/6309.pdf |