Anti-Infective and Anti-Inflammatory Mode of Action of Peptide 19-2.5

Anti-Infective and Anti-Inflammatory Mode of Action of Peptide 19-2.5

The polypeptide Pep19-2.5 (Aspidasept<sup>®</sup>) has been described to act efficiently against infection-inducing bacteria by binding and neutralizing their most potent toxins, i.e., lipopolysaccharides (LPS) and lipoproteins/peptides (LP), independent of the resistance status of the b...

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Bibliographic Details
Main Authors: Lena Heinbockel, Günther Weindl, Wilmar Correa, Julius Brandenburg, Norbert Reiling, Karl-Heinz Wiesmüller, Tobias Schürholz, Thomas Gutsmann, Guillermo Martinez de Tejada, Karl Mauss, Klaus Brandenburg
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
Aspidasept
lipopolysaccharide
antimicrobial peptides
pathogen-associated patterns
pharmacodynamics
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/3/1465

Internet

https://www.mdpi.com/1422-0067/22/3/1465

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