CTHRSSVVC Peptide as a Possible Early Molecular Imaging Target for Atherosclerosis

The purpose of our work was to select phages displaying peptides capable of binding to vascular markers present in human atheroma, and validate their capacity to target the vascular markers in vitro and in low-density lipoprotein receptor knockout (LDLr−/−) mouse model of atherosclerosis. By peptide...

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Bibliographic Details
Main Authors: Rosemeire A. Silva, Ricardo J. Giordano, Paulo S. Gutierrez, Viviane Z. Rocha, Martina Rudnicki, Patrick Kee, Dulcinéia S. P. Abdalla, Pedro Puech-Leão, Bruno Caramelli, Wadih Arap, Renata Pasqualini, José C. Meneghetti, Fabio L. N. Marques, Menka Khoobchandani, Kattesh V. Katti, Ademar B. Lugão, Jorge Kalil
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/9/1383