Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity.

Borrelia burgdorferi, the pathogen of Lyme disease, cycles in nature through Ixodes ticks and mammalian hosts. At least five Complement Regulator-Acquiring Surface Proteins (BbCRASPs) are produced by B. burgdorferi, which are thought to assist spirochetes in host immune evasion. Recent studies estab...

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Bibliographic Details
Main Authors: Adam S Coleman, Xiuli Yang, Manish Kumar, Xinyue Zhang, Kamoltip Promnares, Deborah Shroder, Melisha R Kenedy, John F Anderson, Darrin R Akins, Utpal Pal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2526170?pdf=render