Apoptotic Volume Decrease (AVD) Is Independent of Mitochondrial Dysfunction and Initiator Caspase Activation

Persistent cell shrinkage is a major hallmark of apoptotic cell death. The early-phase shrinkage, which starts within 30−120 min after apoptotic stimulation and is called apoptotic volume decrease (AVD), is known to be accomplished by activation of K+ channels and volume-sensitive outwardly rectifyi...

Full description

Bibliographic Details
Main Authors: Takeshi Tsubata, Emi Maeno, Yasunobu Okada
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Cells
Subjects:
AVD
Online Access:http://www.mdpi.com/2073-4409/1/4/1156