Recombinant Expression and Functional Characterization of Martentoxin: A Selective Inhibitor for BK Channel (α + β4)

Martentoxin (MarTX), a 37-residue peptide purified from the venom of East-Asian scorpion (Buthus martensi Karsch), was capable of blocking large-conductance Ca2+-activated K+ (BK) channels. Here, we report an effective expression and purification approach for this toxin. The cDNA encoding martentox...

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Bibliographic Details
Main Authors: Jie Tao, Zhi Lei Zhou, Bin Wu, Jian Shi, Xiao Ming Chen, Yong Hua Ji
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/6/4/1419