Role of AE2 for pHi regulation in biliary epithelial cells

The Cl-/HCO3- anion exchanger 2 (AE2) is known to be involved in intracellular pH (pHi) regulation and transepithelial acid-base transport. Early studies showed that AE2 gene expression is reduced in liver biopsies and blood mononuclear cells from patients with primary biliary cirrhosis (PBC), a dis...

Full description

Bibliographic Details
Main Authors: Axel R. Concepcion, María eLopez, Alberto eArdura-Fabregat, Juan F. Medina
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00413/full