Transcriptomic and proteomic host response to Aspergillus fumigatus conidia in an air-liquid interface model of human bronchial epithelium.

Aspergillus fumigatus (A. fumigatus) is a wide-spread fungus that is a potent allergen in hypersensitive individuals but also an opportunistic pathogen in immunocompromised patients. It reproduces asexually by releasing airborne conidiospores (conidia). Upon inhalation, fungal conidia are capable of...

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Bibliographic Details
Main Authors: Amreen Toor, Luka Culibrk, Gurpreet K Singhera, Kyung-Mee Moon, Anna Prudova, Leonard J Foster, Margo M Moore, Delbert R Dorscheid, Scott J Tebbutt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209652