Non-RBM Mutations Impaired SARS-CoV-2 Spike Protein Regulated to the ACE2 Receptor Based on Molecular Dynamic Simulation

Non-RBM Mutations Impaired SARS-CoV-2 Spike Protein Regulated to the ACE2 Receptor Based on Molecular Dynamic Simulation

The emergence of novel coronavirus mutants is a main factor behind the deterioration of the epidemic situation. Further studies into the pathogenicity of these mutants are thus urgently needed. Binding of the spinous protein receptor binding domain (RBD) of SARS-CoV-2 to the angiotensin-converting e...

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Bibliographic Details
Main Authors: Yaoqiang Du, Hao Wang, Linjie Chen, Quan Fang, Biqin Zhang, Luxi Jiang, Zhaoyu Wu, Yexiaoqing Yang, Ying Zhou, Bingyu Chen, Jianxin Lyu, Zhen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
SARS-CoV-2
spike protein
non-RBM mutations
ACE2 receptor
molecular dynamic simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.614443/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.614443/full

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