Determination of FVIIa-sTF Inhibitors in Toxic Microcystis Cyanobacteria by LC-MS Technique

The blood coagulation cascade involves the human coagulation factors thrombin and an activated factor VII (fVIIa). Thrombin and fVIIa are vitamin-K-dependent clotting factors associated with bleeding, bleeding complications and disorders. Thrombin and fVIIa cause excessive bleeding when treated with...

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Bibliographic Details
Main Authors: Andrea Roxanne J. Anas, Anna Nakajima, Chiaki Naruse, Mineka Tone, Hirohiko Asukabe, Ken-ichi Harada
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/14/1/7