<i>MYC</i> DNA Methylation in Prostate Tumor Tissue Is Associated with Gleason Score

<i>MYC</i> DNA Methylation in Prostate Tumor Tissue Is Associated with Gleason Score

Increasing evidence suggests a role of epigenetic mechanisms at chromosome 8q24, an important cancer genetic susceptibility region, in prostate cancer. We investigated whether <i>MYC</i> DNA methylation at 8q24 (six CpG sites from exon 3 to the 3′ UTR) in prostate tumor was associated wi...

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Bibliographic Details
Main Authors: Kathryn Hughes Barry, Kareshma Mohanty, Patricia A. Erickson, Difei Wang, Jianxin Shi, Gary Rose, Ashley Cellini, Kimberly Clark, Nicholas Ambulos, Jing Yin, Liying Yan, Matthew Poulin, Ann Meyer, Yuji Zhang, Søren M. Bentzen, Allen Burke, Arif Hussain, Sonja I. Berndt
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Genes
Subjects:
aggressive disease
DNA methylation
Gleason score (GS)
MYC
non-coding RNAs (ncRNAs)
prostate cancer
Online Access:https://www.mdpi.com/2073-4425/12/1/12

Internet

https://www.mdpi.com/2073-4425/12/1/12

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