Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway

Abstract Background Atherosclerosis is a condition with the vascular accumulation of lipid plaques, and its main major contributing factor is endothelial injury induced by oxidized low-density lipoprotein (ox-LDL). Salidroside (SAL) is the primary active ingredient of Rhodiola rosea, and exhibits an...

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Bibliographic Details
Main Authors: Zhongsheng Zhu, Jinyu Li, Xiaorong Zhang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Atherosclerosis
Salidroside (SAL)
Oxidized low-density lipoprotein (ox-LDL)
Endothelial cell
Oxidative stress
Autophagy
Online Access:http://link.springer.com/article/10.1186/s12906-019-2526-4

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http://link.springer.com/article/10.1186/s12906-019-2526-4

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