c-Myc—Dependent Formation of Robertsonian Translocation Chromosomes in Mouse Cells
Robertsonian (Rb) translocation chromosomes occur in human and murine cancers and involve the aberrant joining of two acrocentric chromosomes in humans and two telocentric chromosomes in mice. Mechanisms leading to their generation remain elusive, but models for their formation have been proposed....
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-07-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558607800832 |