c-Myc—Dependent Formation of Robertsonian Translocation Chromosomes in Mouse Cells

Robertsonian (Rb) translocation chromosomes occur in human and murine cancers and involve the aberrant joining of two acrocentric chromosomes in humans and two telocentric chromosomes in mice. Mechanisms leading to their generation remain elusive, but models for their formation have been proposed....

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Bibliographic Details
Main Authors: Amanda Guffei, Zelda Lichtensztejn, Amanda Gonçlves {ptdos} Santos Silva, Sherif F. Louis, Andrea Caporali, Sabine Mai
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800832