Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes

Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes

ABCB4 is necessary for the secretion of phospholipids from hepatocytes into bile and for the protection of cell membranes against bile salts. Lipid rafts are plasma membrane microdomains containing high contents of cholesterol and sphingolipids, which are separated by Triton X-100 extraction or Opti...

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Bibliographic Details
Main Authors: Shin-ya Morita, Tadanori Tsuda, Manami Horikami, Reiko Teraoka, Shuji Kitagawa, Tomohiro Terada
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Journal of Lipid Research
Subjects:
raft
phosphatidylcholine
phosphatidylethanolamine
sphingomyelin
cholesterol
ABC transporter
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520421613

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http://www.sciencedirect.com/science/article/pii/S0022227520421613

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