Co-Localization of Hammerhead Ribozymes and HIV RNA’s by Rev Multimerization
To effectively apply Hammerhead ribozymes as therapeutic agents it is necessary to co-localize them with the desired target. Human immunodeficiency virus type-1 (HIV-1) infectivity is dependent on env gene expression. HIV-1 Rev protein binds to a higher ordered RNA structure within the env transcrip...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Bilimsel Tip Yayinevi
2004-06-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2004-9-2-106-118.pdf |