Atelectasis, Shunt, and Worsening Oxygenation Following Reduction of Respiratory Rate in Healthy Pigs Undergoing ECMO: An Experimental Lung Imaging Study

Atelectasis, Shunt, and Worsening Oxygenation Following Reduction of Respiratory Rate in Healthy Pigs Undergoing ECMO: An Experimental Lung Imaging Study

Rationale: Reducing the respiratory rate during extracorporeal membrane oxygenation (ECMO) decreases the mechanical power, but it might induce alveolar de-recruitment. Dissecting de-recruitment due to lung edema vs. the fraction due to hypoventilation may be challenging in injured lungs.Objectives:...

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Bibliographic Details
Main Authors: Elena Spinelli, Giulia Colussi, Gaia Dal Santo, Eleonora Scotti, Ines Marongiu, Erica Garbelli, Alessandra Mazzucco, Daniele Dondossola, Raquel Maia, Michele Battistin, Osvaldo Biancolilli, Lorenzo Rosso, Stefano Gatti, Tommaso Mauri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
extracorporeal membrane oxygenation
respiratory rate
atelectasis
shunt
expiratory time
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.663313/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.663313/full

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