Impact of index hopping and bias towards the reference allele on accuracy of genotype calls from low-coverage sequencing
Abstract Background Inherent sources of error and bias that affect the quality of sequence data include index hopping and bias towards the reference allele. The impact of these artefacts is likely greater for low-coverage data than for high-coverage data because low-coverage data has scant informati...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | deu |
| Published: |
BMC
2018-12-01
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| Series: | Genetics Selection Evolution |
| Online Access: | http://link.springer.com/article/10.1186/s12711-018-0436-4 |