A novel replication-competent vaccinia vector MVTT is superior to MVA for inducing high levels of neutralizing antibody via mucosal vaccination.

Mucosal vaccination offers great advantage for inducing protective immune response to prevent viral transmission and dissemination. Here, we report our findings of a head-to-head comparison of two viral vectors modified vaccinia Ankara (MVA) and a novel replication-competent modified vaccinia Tian T...

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Bibliographic Details
Main Authors: Xiaoxing Huang, Bin Lu, Wenbo Yu, Qing Fang, Li Liu, Ke Zhuang, Tingting Shen, Haibo Wang, Po Tian, Linqi Zhang, Zhiwei Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2613559?pdf=render