Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer

Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer

Enteric glia are a distinct population of peripheral glial cells in the enteric nervous system that regulate intestinal homeostasis, epithelial barrier integrity, and gut defense. Given these unique attributes, we investigated the impact of enteric glia depletion on tumor development in azoxymethane...

Full description

Bibliographic Details
Main Authors: Robert Yuan, Nupur Bhattacharya, Justin A. Kenkel, Jeanne Shen, Michael A. DiMaio, Sreya Bagchi, Tyler R. Prestwood, Aida Habtezion, Edgar G. Engleman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
enteric glia
colorectal cancer
azoxymethane/dextran sodium sulfate
ApcMin/+
enteric nervous system
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.595892/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.595892/full

Similar Items