ECM-enriched alginate hydrogels for bioartificial pancreas: an ideal niche to improve insulin secretion and diabetic glucose profile

Introduction: The success of a bioartificial pancreas crucially depends on ameliorating encapsulated beta cells survival and function. By mimicking the cellular in vivo niche, the aim of this study was to develop a novel model for beta cells encapsulation capable of establishing an appropriate micro...

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Bibliographic Details
Main Authors: Joana Crisóstomo, Ana M Pereira, Sílvia J Bidarra, Ana C Gonçalves, Pedro L Granja, Jorge FJ Coelho, Cristina C Barrias, Raquel Seiça
Format: Article
Language:English
Published: SAGE Publishing 2019-10-01
Series:Journal of Applied Biomaterials & Functional Materials
Online Access:https://doi.org/10.1177/2280800019848923