Mitochondria, Cognitive Impairment, and Alzheimer's Disease
To date, the beta amyloid (Aβ) cascade hypothesis remains the main pathogenetic model of Alzheimer's disease (AD), but its role in the majority of sporadic AD cases is unclear. The “mitochondrial cascade hypothesis” could explain many of the biochemical, genetic, and pathological features of sp...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2009-01-01
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Series: | International Journal of Alzheimer's Disease |
Online Access: | http://dx.doi.org/10.4061/2009/951548 |