Conversion of mesenchymal stem cells into a canine hepatocyte-like cells by Foxa1 and Hnf4a

Introduction: Hepatocytes, which account for the majority of liver tissue, are derived from the endoderm and become hepatocytes via differentiation of hepatic progenitor cells. Induced hepatocyte-like (iHep) cells and artificial liver tissues are expected to become useful, efficient therapies for se...

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Bibliographic Details
Main Authors: Suguru Nitta, Yuto Kusakari, Yoko Yamada, Takeaki Kubo, Sakurako Neo, Hirotaka Igarashi, Masaharu Hisasue
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Regenerative Therapy
Subjects:
Dog
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300031