Potential errors in conventional DOT measurement techniques in shake flasks and verification using a rotating flexitube optical sensor

<p>Abstract</p> <p>Background</p> <p>Dissolved oxygen tension (DOT) is an important parameter for evaluating a bioprocess. Conventional means to measure DOT in shake flasks using fixed Clark-type electrodes immersed in the bulk liquid are problematic, because they inher...

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Bibliographic Details
Main Authors: Käser Andreas, Kensy Frank, Hansen Sven, Büchs Jochen
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/49