Reciprocal role of cyclins and cyclin kinase inhibitor p21<sup>WAF1/CIP1 </sup>on lymphocyte proliferation, allo-immune activation and inflammation
<p>Abstract</p> <p>Background</p> <p>Immune activation that results due to the aberrant proliferation of lymphocytes leads to inflammation and graft rejection in organ transplant recipients. We hypothesize that the cell cycle control and inflammation are parallel events...
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Format: | Article |
Language: | English |
Published: |
BMC
2005-09-01
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Series: | BMC Immunology |
Online Access: | http://www.biomedcentral.com/1471-2172/6/22 |