Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGFβ1 or M-CSF.

Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGFβ1 or M-CSF.

The chemokine Interferon gamma-induced protein 10 (IP-10) and human leukocyte antigen (HLA) are widely used indicators of glial activation and neuroinflammation and are up-regulated in many brain disorders. These inflammatory mediators have been widely studied in rodent models of brain disorders, bu...

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Bibliographic Details
Main Authors: Amy M Smith, E Scott Graham, Sheryl Xia Feng, Robyn L Oldfield, Peter M Bergin, Edward W Mee, Richard L M Faull, Maurice A Curtis, Mike Dragunow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855168?pdf=render

Internet

http://europepmc.org/articles/PMC3855168?pdf=render

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