High-resolution array CGH profiling identifies Na/K transporting ATPase interacting 2 (NKAIN2) as a predisposing candidate gene in neuroblastoma.

Neuroblastoma (NB), the most common solid cancer in early childhood, usually occurs sporadically but also its familial occurance is known in 1-2% of NB patients. Germline mutations in the ALK and PHOX2B genes have been found in a subset of familial NBs. However, because some individuals harbouring m...

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Bibliographic Details
Main Authors: Paolo Romania, Aurora Castellano, Cecilia Surace, Arianna Citti, Maria Antonietta De Ioris, Pietro Sirleto, Marilena De Mariano, Luca Longo, Renata Boldrini, Adriano Angioni, Franco Locatelli, Doriana Fruci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3808344?pdf=render