Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells

Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells

Dental pulp stem cells (DPSCs) from adult teeth show the expression of a very complete repertoire of stem pluripotency core factors and a high plasticity for cell reprogramming. Canonical Wnt and Notch signaling pathways regulate stemness and the expression of pluripotency core factors in DPSCs, and...

Full description

Bibliographic Details
Main Authors: Verónica Uribe-Etxebarria, Patricia García-Gallastegui, Miguel Pérez-Garrastachu, María Casado-Andrés, Igor Irastorza, Fernando Unda, Gaskon Ibarretxe, Nerea Subirán
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
dental pulp stem cells
chromatin remodeling
cell cycle
pluripotency
dna methylation
histone acetylation
histone methylation
notch pathway
wnt pathway
Online Access:https://www.mdpi.com/2073-4409/9/3/652

Internet

https://www.mdpi.com/2073-4409/9/3/652

Similar Items