YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial-mesenchymal transition

Abstract Background N 6-methyladenosine (m6A) modification, as the most abundant RNA modification, widely participates in the physiological process and is involved in multiple disease progression, especially cancer. YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) is a pivotal m6A “reader” prot...

Full description

Bibliographic Details
Main Authors: Xiangyuan Luo, Mengdie Cao, Fan Gao, Xingxing He
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Experimental Hematology & Oncology
Subjects:
m6A
EMT
Online Access:https://doi.org/10.1186/s40164-021-00227-0