Preparation of a First <sup>18</sup>F-Labeled Agonist for M<sub>1</sub> Muscarinic Acetylcholine Receptors

Preparation of a First <sup>18</sup>F-Labeled Agonist for M<sub>1</sub> Muscarinic Acetylcholine Receptors

M<sub>1</sub> muscarinic acetylcholine receptors (mAChRs) are abundant in postsynaptic nerve terminals of all forebrain regions and have been implicated in the cognitive decline associated with Alzheimer’s disease and other CNS pathologies. Consequently, major efforts have been spent in...

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Bibliographic Details
Main Authors: Boris D. Zlatopolskiy, Felix Neumaier, Till Rüngeler, Birte Drewes, Niklas Kolks, Bernd Neumaier
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
radiolabeling
fluorine-18
positron emission tomography
acetylcholine receptor agonist
Cu-mediated radiofluorination
Online Access:https://www.mdpi.com/1420-3049/25/12/2880

Internet

https://www.mdpi.com/1420-3049/25/12/2880

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