LncIRS1 controls muscle atrophy via sponging miR‐15 family to activate IGF1‐PI3K/AKT pathway

LncIRS1 controls muscle atrophy via sponging miR‐15 family to activate IGF1‐PI3K/AKT pathway

Abstract Background Recent studies indicate important roles for long noncoding RNAs (lncRNAs) in the regulation of gene expression by acting as competing endogenous RNAs (ceRNAs). However, the specific role of lncRNAs in skeletal muscle atrophy is still unclear. Our study aimed to identify the funct...

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Bibliographic Details
Main Authors: Zhenhui Li, Bolin Cai, Bahareldin Ali Abdalla, Xuenong Zhu, Ming Zheng, Peigong Han, Qinghua Nie, Xiquan Zhang
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Atrophy
ceRNA
IRS1
Myogenesis
lncRNA‐miRNA‐gene network
Online Access:https://doi.org/10.1002/jcsm.12374

Internet

https://doi.org/10.1002/jcsm.12374

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