“Ways in which the neonatal Fc-receptor is involved in autoimmunity”

Since the neonatal IgG Fc receptor (FcRn) was discovered, its role has evolved from immunoglobulin recycling and biodistribution to antigen presentation and immune complex routing, bringing it to the center of both humoral and cellular immune responses. FcRn is thus involved in the pathophysiology o...

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Bibliographic Details
Main Authors: Juliette Lamamy, Pierre Boulard, Guillaume Brachet, Sébastien Tourlet, Valérie Gouilleux-Gruart, Yanis Ramdani
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Translational Autoimmunity
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909021000423