Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors.

Adenocarcinomas located near the gastroesophageal junction have unclear etiology and are difficult to classify. We used DNA methylation analysis to identify subtype-specific markers and new subgroups of gastroesophageal adenocarcinomas, and studied their association with epidemiological risk factors...

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Bibliographic Details
Main Authors: Xinhui Wang, Gyeong Hoon Kang, Mihaela Campan, Daniel J Weisenberger, Tiffany I Long, Wendy Cozen, Leslie Bernstein, Anna H Wu, Kimberly D Siegmund, Darryl Shibata, Peter W Laird
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3197593?pdf=render