The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice

The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice

Short-and long-term exposure to particulate matter (PM) has been associated with cardiovascular disease (CVD). It is well recognized that oxidative stress is a potential major mechanism in PM-induced vascular injuries, in which the nuclear factor E2-related factor 2 (Nrf2) signaling pathway plays a...

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Bibliographic Details
Main Authors: Mengyu Gao, Yuanyuan Ma, Jing Luo, Daochuan Li, Menghui Jiang, Qixiao Jiang, Jingbo Pi, Rui Chen, Wen Chen, Rong Zhang, Yuxin Zheng, Lianhua Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
Pm
AngII
Nrf2
endothelia cell dysfunction
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.618023/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.618023/full

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